February 4, 1454 – In the Thirteen Years’ War, the Secret Council of the Prussian Confederation sends a formal act of disobedience to the Grand Master.

March 6, 1454 – Thirteen Years’ War: Delegates of the Prussian Confederation pledge allegiance to King Casimir IV of Poland who agrees to commit his forces in aiding the Confederation’s struggle for independence from the Teutonic Knights.

September 18, 1454 – In the Battle of Chojnice, the Polish army is defeated by the Teutonic army during the Thirteen Years’ War.

March 9, 1454 – Amerigo Vespucci, Italian explorer and cartographer (d. 1512)

July 14, 1454 – Poliziano, Florentine humanist (d. 1494)

September 4, 1454 – Henry Stafford, 2nd Duke of Buckingham, English politician (d. 1483)

November 25, 1454 – Queen Catherine Cornaro of Cyprus (d. 1510)